Oshoala scored a brace for Barcelona as they smashed the Madrid CFF 4-0 and kept their unbeaten start to the Primera Division Femenina.
She opened the score just before half time and doubled the away side advantage three minutes after the break.
Two more goals were scored, Jennifer Hermoso and Aitana Bonmati, as Barcelona recorded an emphatic victory over their rivals to stay at the top of the division in 19 points alongside Deportivo Abanca.
Asisat Oshoala has scored eight goals in 11 appearances for the season in five consecutive games.
Watch the highlights on FC Barcelona Femení’s Twitter account